Methodology · Updated 10 October 2026

Health claims should survive contact with the evidence.

MPSANO translates public research into general health education. The method below explains how claims are selected, limited and corrected before they become practical guidance.

The MPSANO research standard

A recommendation should show its work.

“Evidence-based” is not a badge. It is a sequence of decisions that limits what we are allowed to claim.

Read the full methodology
01

Define the claim

Turn a broad health promise into a question with a measurable outcome.

02

Rank the evidence

Prioritize reviews, guidelines and controlled human research over mechanisms alone.

03

Pressure-test it

Check dose, population, duration, conflicts, limitations and what the intervention replaces.

04

Translate carefully

Separate supported action from plausible interpretation and state meaningful uncertainty.

Human outcomes outrank dramatic mechanismsContradictory evidence stays visibleEducational boundaries stay explicitFactual corrections remain open

Evidence hierarchy

Different sources answer different questions.

The highest available tier does not automatically settle a claim. Quality, relevance and consistency still matter.

Highest decision weightSystematic reviews · guidelines

Synthesize multiple relevant studies and recommendations.

Direct intervention evidenceControlled human trials

Test what changed under defined conditions.

Pattern detectionObservational human data

Find associations without automatically proving cause.

Mechanism and hypothesisAnimal · cell · mechanistic research

Explain plausibility without proving a human outcome.

Always labelled separatelyMPSANO interpretation

Practical synthesis that may not be a settled scientific conclusion.

What we do

Make uncertainty usable.

  • Attach claims to the most relevant evidence level.
  • Distinguish statistical signals from meaningful outcomes.
  • Show practical trade-offs, dose and context.
  • Keep important contradictions visible.

What we do not do

Turn education into diagnosis.

  • No individual diagnosis or treatment.
  • No personal medication or hormone advice.
  • No certainty stronger than the evidence.
  • No hidden supplement or affiliate stack.

Corrections stay open

Found a factual problem?

Research changes, and editorial mistakes can happen. Send the exact claim, the relevant source and where it appears. We review substantive corrections and may update the material without promising a fixed release cycle.

Submit a correction